%0 Journal Article
%T Vaccine-induced thrombotic thrombocytopenia following coronavirus vaccine: A narrative review.
%A Ahmed SH
%A Shaikh TG
%A Waseem S
%A Qadir NA
%A Yousaf Z
%A Ullah I
%J Ann Med Surg (Lond)
%V 73
%N 0
%D Jan 2022
%M 34745596
暂无%R 10.1016/j.amsu.2021.102988
%X The novel coronavirus pandemic has taken a toll on the global healthcare systems and economy. Safety precautions, along with vaccination, are the most effective preventive measures. The global vaccination program against COVID-19 has dramatically reduced the number of deaths and cases. However, the incidence of thrombotic events and thrombocytopenia post-COVID-19 vaccination known as vaccine-induced thrombotic thrombocytopenia has raised safety concerns. This has led to an element of vaccine hesitancy. The exact mechanism for vaccine-induced thrombotic thrombocytopenia is unknown. Although the incidence of thrombosis associated with COVID-19 vaccination is low, it still requires attention, especially in older people, smokers, and people with preexisting comorbidities. This study aims to review the pathophysiology, diagnosis, and management of vaccine-induced thrombotic thrombocytopenia, to provide a concise and comprehensive update.