%0 Journal Article
%T A Case of Hematochezia Due to Panitumumab-induced Colitis with Vitamin K Deficiency.
%A Tamura H
%A Nakashima K
%A Uchiyama N
%A Ogawa S
%A Hatada H
%A Yoshida N
%A Uchida K
%A Ozono Y
%A Tanaka H
%A Yamamto K
%A Kawakami H
%J Intern Med
%V 0
%N 0
%D Nov 2021 6
%M 34744108
%F 1.282
%R 10.2169/internalmedicine.8254-21
%X Panitumumab, a fully human anti-epidermal growth factor receptor (EGFR) monoclonal antibody, has been shown to be useful in treating either advanced or recurrent KRAS/NRAS/BRAF wild-type colorectal cancer. We herein report the case of a 60-year-old man with short bowel syndrome who developed hematochezia due to panitumumab-induced colitis with vitamin K deficiency during third-line chemotherapy. The cause of vitamin K deficiency was the lack of intravenous vitamin K supplementation following a change from central venous nutrition to peripheral venous nutrition. We advise clinicians to carefully check for colitis and manage the infusions of chemotherapy patients with short bowel syndrome.