%0 Journal Article %T Locked-in Syndrome Due to Meningovascular Syphilis: A Case Report and Literature Review. %A Yokota Y %A Ishihara M %A Ninomiya S %A Mitsuke K %A Kamei S %A Nakajima H %J Intern Med %V 0 %N 0 %D Oct 2021 19 %M 34670896 %F 1.282 %R 10.2169/internalmedicine.8269-21 %X We herein report a 46-year-old man presenting with locked-in syndrome secondary to meningovascular syphilis. Brain magnetic resonance imaging (MRI) demonstrated multiple acute infarctions in the left ventromedial pons, right basis pontis, and left basal ganglia. His locked-in syndrome was hypothesized to have been caused by thrombosis of the small paramedian branches of the basilar artery due to syphilitic arteritis. This is a unique case of bilateral ventromedial pontine infarction caused by meningovascular syphilis that presented as locked-in syndrome. Meningovascular syphilis should be included in the differential diagnosis of uncommon stroke, particularly in young men.