%0 Case Reports
%T Systemic AA Amyloidosis Associated With Intravenous Injection of Oral Prescription Opioids-An Autopsy Case Report.
%A Zabel KM
%A Lin GY
%A Sell RE
%A Aisagbonhi O
%J Am J Forensic Med Pathol
%V 43
%N 2
%D Jun 2022 1
%M 34510052
%F 1.108
%R 10.1097/PAF.0000000000000718
%X <B>UNASSIGNED: </B>There are reports of AA amyloidosis associated with intravenous and/or subcutaneous injection of street drugs, such as heroin and cocaine. Most reports describe patients with substance use disorder, renal amyloidosis and concurrent viral infections, such as hepatitis and/or human immunodeficiency virus. Herein, we present a case of systemic AA amyloidosis and sepsis in a 34-year-old woman with a history of intravenous injection of oral prescription medications (as evidenced by excipient lung disease) who had no known history of human immunodeficiency virus nor of hepatitis B or C. Our case shows the broader spectrum of pathology that can occur with the misuse of prescription medications.