%0 Journal Article
%T The innervation of the bladder, the pelvic floor, and emotion: A review.
%A Quaghebeur J
%A Petros P
%A Wyndaele JJ
%A De Wachter S
%J Auton Neurosci
%V 235
%N 0
%D 11 2021
%M 34391125
%F 2.355
%R 10.1016/j.autneu.2021.102868
%X The innervation of the pelvic region is complex and includes extensive neurologic pathways. The higher centres' organisation determining the pelvic floor and organs' function remains a challenge understanding the physiological and pain mechanisms. Psychological and emotional factors have a profound influence on the pelvic floor and organ dysfunction such as LUTS. LUTS are associated with stress, depression, and anxiety. Neuroception is a subconscious neuronal system for detecting threats and safety and might explain the permanent disturbance of higher brain centres maintaining functional urological and gastrointestinal disorders and sphincter dysfunction.