%0 Journal Article
%T Xanthogranulomatous pyelonephritis: A rare case report of a 54 year old female (a potentially fatal infection).
%A Gri J
%A Hatahet MA
%A Chopra S
%J Int J Surg Case Rep
%V 85
%N 0
%D Aug 2021
%M 34388912
暂无%R 10.1016/j.ijscr.2021.106287
%X <B>UNASSIGNED: </B>Xanthogranulomatous pyelonephritis (XPGN) is a rare pathology of the kidneys occurring in 0.6 to 1% of all cases of renal infections, in both men and women. It is characterized by severe inflammation of the renal parenchyma leading to formation of granulomatous tissue containing lipid-laden macrophages. This condition may mimic less aggressive or benign conditions but may worsen or be fatal if not treated aggressively.<BR><B>METHODS: </B>Our patient is a 54 year old Caucasian female who presented with five days of left flank pain, hematuria, chills, nausea and vomiting. Imaging and biopsy results showed that the patient had XPGN.<BR><B>UNASSIGNED: </B>XPGN is a difficult condition to diagnose as the symptoms are non-specific relative to renal cell carcinoma or other common renal infections. Definitive diagnosis is made with a biopsy; however, clues in various imaging modalities are used to make a tentative diagnosis. It is unclear whether earlier surgical intervention would have improved overall patient outcomes. Currently, a partial or complete nephrectomy is the only effective treatment.<BR><B>CONCLUSIONS: </B>Aggressive management including early diagnosis, antibiotics and nephrectomy appears to be critical in preventing progression and complications of XPNG.