%0 Journal Article
%T Viridans Group Streptococci in Pediatric Leukemia and Stem Cell Transplant: Review of a Risk-stratified Guideline for Empiric Vancomycin in Febrile Neutropenia.
%A Ruhayel SD
%A Foley DA
%A Hamilton K
%A Ferguson P
%A Kotecha RS
%A Bowen AC
%A Yeoh DK
%J Pediatr Infect Dis J
%V 40
%N 9
%D 09 2021 1
%M 34285167
%F 3.806
%R 10.1097/INF.0000000000003210
%X Viridans group streptococci (VGS) are an important cause of sepsis in immunosuppressed children. We reviewed the effectiveness of risk-stratified addition of vancomycin to empiric febrile neutropenia therapy among 107 children with leukemia or undergoing an allogeneic transplant. Of 19 VGS bacteremia episodes, 78.9% were susceptible to risk-stratified antibiotics including 100% from high-risk patients. All blood cultures were flagged positive within 24 hours.