%0 Journal Article
%T Systemic oxidative stress biomarkers in patients with vitreomacular traction syndrome.
%A Kilic D
%A Kocer D
%A Sırakaya E
%A Küçük B
%A Vural E
%A Guven S
%A Duru N
%J Int Ophthalmol
%V 41
%N 11
%D Nov 2021
%M 34259960
%F 2.029
%R 10.1007/s10792-021-01949-0
%X <B>OBJECTIVE: </B>To evaluate whether the systemic oxidative stress biomarkers increased in patients with vitreomacular traction syndrome (VMT).<BR><B>METHODS: </B>This study compared 25 patients diagnosed with VMT with 20 healthy controls. As a biomarker of systemic oxidative stress, malondialdehyde (MDA) was measured. Total oxidant status (TOS) and total antioxidant status (TAS) were measured to evaluate the systemic oxidant status.<BR><B>RESULTS: </B>Serum MDA values were significantly higher among the patients (p < 0.001). The ideal cut-off value for MDA was determined to be 22.1 µmol/L, with 80% sensitivity and 75% specificity. The between-group differences were not statistically significant for TOS or TAS (p = 0.326 and p = 0.698, respectively).<BR><B>CONCLUSIONS: </B>Increased MDA levels suggest that systemic oxidative stress may play a role in VMT.