%0 Case Reports
%T A case of reversible cerebral vasoconstriction syndrome associated with anti-phospholipid antibody syndrome and systemic lupus erythematosus.
%A Shima A
%A Maki T
%A Mimura N
%A Yamashita H
%A Emoto N
%A Yoshifuji H
%A Takahashi R
%J eNeurologicalSci
%V 24
%N 0
%D Sep 2021
%M 34258413
暂无%R 10.1016/j.ensci.2021.100351
%X The pathomechanisms and treatment strategy for rare presentations of reversible cerebral vasoconstriction syndrome (RCVS) with anti-phospholipid syndrome (APS) remain to be determined. We report a 67-year-old woman with APS who presented with ischemic stroke due to RCVS. She was treated with low-dose cilostazol and lomerizine hydrochloride, which resulted in functional improvement and recovery of vasoconstriction within 12 weeks. Her plasma endothelin-1 level was decreased after relief of vasoconstriction, compared with the pre-treatment condition. Increased plasma endothelin-1 may be related to the underlying pathomechanism of RCVS with APS, against which cilostazol and lomerizine hydrochloride could be effective.