%0 Journal Article
%T Zebrafish as a New Model to Study the Crosstalk between Tumor and Host Metabolism.
%A Montal E
%A White RM
%J Trends Cancer
%V 7
%N 8
%D 08 2021
%M 34244124
%F 19.161
%R 10.1016/j.trecan.2021.06.006
%X The mechanism of metabolic crosstalk between different tissues in the host remains poorly understood but is likely to play important roles in tumor growth and cachexia. A recent study from Naser, Jackstadt, et al. utilizes isotope tracing in a zebrafish melanoma model and finds that tumors secrete alanine into circulation, which is taken up by the liver and used for gluconeogenesis.