%0 Journal Article
%T Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study.
%A Escrihuela-Vidal F
%A López-Cortés LE
%A Escolà-Vergé L
%A De Alarcón González A
%A Cuervo G
%A Sánchez-Porto A
%A Fernández-Hidalgo N
%A Luque R
%A Montejo M
%A Miró JM
%A Goenaga MÁ
%A Muñoz P
%A Valerio M
%A Ripa M
%A Sousa-Regueiro D
%A Gurguí M
%A Fariñas-Alvarez MC
%A Mateu L
%A García Vázquez E
%A Gálvez-Acebal J
%A Carratalà J
%A  
%J Open Forum Infect Dis
%V 8
%N 6
%D Jun 2021
%M 34189163
%F 4.423
%R 10.1093/ofid/ofab163
%X <B>UNASSIGNED: </B>Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption.<BR><B>UNASSIGNED: </B>We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG) was performed in a 1:2 matched analysis.<BR><B>UNASSIGNED: </B>Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When comparing SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, P = .116); valve disorder, including perforation (22.2% vs 18.1%, P = .584), pseudoaneurysm (16.7% vs 8.3%, P = .108), or prosthesis dehiscence (1.4% vs 6.3%, P = .170); paravalvular complications, including abscess (25% vs 18.8%, P = .264) and intracardiac fistula (5.6% vs 3.5%, P = .485); heart failure (34.7% vs 38.9%, P = .655); or embolic events (41.7% vs 32.6%, P = .248). Indications for surgery (70.8% vs 70.8%; P = 1) and mortality (13.9% vs 16.7%; P = .741) were similar between groups.<BR><B>UNASSIGNED: </B>SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.