%0 Journal Article %T The silent pandemic in South Africa: Extra-pulmonary tuberculosis from head to heel. %A Le Roux CE %A Vlok SSC %J SA J Radiol %V 25 %N 1 %D 2021 %M 33936795 暂无%R 10.4102/sajr.v25i1.2026 %X Extra-pulmonary tuberculosis (EPTB), caused by Mycobacterium tuberculosis, is the leading cause of communicable disease-related deaths in people with human immunodeficiency virus (HIV) worldwide and in South Africa. Mycobacterium tuberculosis disseminates haematogenously from an active primary lung focus and may affect extra-pulmonary sites in up to 15% of patients. Extra-pulmonary TB may present with a normal chest radiograph, which often causes a significant diagnostic dilemma. This review describes the main sites of involvement in EPTB, which is illustrated by local imaging examples.