%0 Journal Article
%T Multidrug resistance: The clinical dilemma of refractory Helicobacter pylori infection.
%A Kuo CJ
%A Lee CH
%A Chang ML
%A Lin CY
%A Lin WR
%A Su MY
%A Chiu CH
%A Tseng CN
%A Wu YS
%A Chiu CT
%A Lai CH
%J J Microbiol Immunol Infect
%V 0
%N 0
%D Mar 2021 23
%M 33840604
%F 10.273
%R 10.1016/j.jmii.2021.03.006
%X This study investigated the antimicrobial resistance of isolates from patients with refractory Helicobacter pylori. The resistance rate was 34.1% for amoxicillin, 92.7% for clarithromycin, 65.9% for metronidazole, 85.4% for levofloxacin, and 29.3% for rifabutin. Dual resistance to both clarithromycin and levofloxacin was found in 73.2%. The antimicrobial resistance rate of refractory H. pylori was extremely high, which had become a major consideration in therapeutic challenge.