%0 Journal Article %T Factors predicting contralateral nodal spread in papillary carcinoma of thyroid. %A Verma H %A Shah N %A Jain P %A Manikantan K %A Sharan R %A Arun P %J Indian J Cancer %V 0 %N 0 %D Jan 2021 27 %M 33753605 %F 1.397 %R 10.4103/ijc.IJC_684_19 %X UNASSIGNED: Lymph node metastasis (LNM) is evident in about 20-50% of cases at presentation in papillary carcinoma thyroid (PTC). There are no clear recommendations for the need and extent of lateral and central compartment dissection in PTC.
UNASSIGNED: A total of 83 patients who underwent total thyroidectomy and bilateral selective neck dissection for diagnosed PTC from September 2011 to October 2017 were retrospectively analyzed.
UNASSIGNED: Tumor site was bilobar or involving isthmus in 40 patients. Contralateral LNM was seen in 42 patients. Both radiological (median size 2.6 cm, P = 0.051) and pathological (median size 3.65 cm, P = 0.015) size of tumor, tumor involving isthmus or bilateral lobes (P = 0.006), and lymphovascular invasion (LVI) (P = 0.026) had significant correlation with contralateral LNM.
UNASSIGNED: Size and site of tumor, ipsilateral lateral compartment nodes involvement, and LVI status of tumor significantly increases the probability of contralateral LNM in patients of PTC.