%0 Journal Article %T Neuroendocrine Tumors of the Thyroid and Their Mimics. %A Livolsi VA %J Endocr Pathol %V 32 %N 2 %D Jun 2021 %M 33687689 %F 4.056 %R 10.1007/s12022-021-09672-3 %X This paper will review neuroendocrine lesions of the thyroid and the differential diagnosis with the most significant such tumor of the thyroid, that is, medullary thyroid carcinoma. A brief overview of the understanding of this tumor's identification as a lesion of C cells and its familial and syndromic associations will be presented. Then, a discussion of the various mimics of medullary carcinoma will be given with an approach to the types of tests that can be done to arrive at a correct diagnostic conclusion. This review will focus on practical "tips" for the practicing pathologist.