%0 Case Reports
%T Case of placental insufficiency and premature delivery in a Fontan pregnancy: physiological insights and considerations on risk stratification.
%A Ordoñez MV
%A Biglino G
%A Caputo M
%A Kelly B
%A Mohan A
%A Trinder J
%A Curtis SL
%J Open Heart
%V 8
%N 1
%D 02 2021
%M 33608474
暂无%R 10.1136/openhrt-2019-001211
%X The coexistence of two complex physiologies such as Fontan and pregnancy is still not fully understood. We aim to add a unique and essential knowledge to help our colleagues in the management of Fontan patients that undergo pregnancy as well as the fetus and the placenta perfusion.<BR>We analyse the coexistence of Fontan and pregnancy physiology on a complex case of a woman with hypoplastic left heart syndrome palliated with a univentricular repair who became pregnant, delivered very prematurely and had atypical placental findings.<BR>Histopathological analysis of the placenta could help us to refine the understanding of Fontan physiology adaptation during pregnancy, predict women and fetal outcomes as well as to plan a better pre-pregnancy status. However, further evidence is needed in order to reach a more solid and unified conclusion.