%0 Case Reports
%T Long-term survival of advanced lung adenocarcinoma by maintenance chemotherapy followed by EGFR-TKI: A case report.
%A Chen HJ
%A Shen JM
%A Lin YN
%A Du W
%A Zhou JP
%A Li QY
%J Medicine (Baltimore)
%V 100
%N 6
%D Feb 2021 12
%M 33578601
%F 1.817
%R 10.1097/MD.0000000000024688
%X <B>BACKGROUND: </B>The incidence of nonsmall cell lung cancer (NSCLC) is high. Most nonsmall cell lung cancers have undergone multiple metastases at the time of initial diagnosis, and the 5 year survival rate is low. At present, comprehensive treatments, including systemic chemotherapy, targeted therapy, antiangiogenic therapy, and immunotherapy, prolong the survival of patients with advanced NSCLC. Herein, we report a case of NSCLC with long-term survival.<BR><B>METHODS: </B>A 61-year-old woman complained of dry cough and shortness of breath and visited our hospital in July 2011. Imaging examination revealed a left upper lung mass with multiple metastases to the liver, adrenal gland, and bone.<BR><B>METHODS: </B>Stage IVB (cT2aN3M1c) lung adenocarcinoma was diagnosed, with multiple metastases of the lymph nodes, liver, adrenal gland, and bone.<BR><B>RESULTS: </B>The patient received systemic chemotherapy and epidermal growth factor receptor-tyrosine kinase inhibitor-targeted therapy, and has survived for more than 9 years.<BR><B>CONCLUSIONS: </B>The patient benefited from maintenance chemotherapy and epidermal growth factor receptor-tyrosine kinase inhibitor treatment and achieved long-term survival.