%0 Journal Article %T Sea Cucumber Derived Type I Collagen: A Comprehensive Review. %A Senadheera TRL %A Dave D %A Shahidi F %J Mar Drugs %V 18 %N 9 %D Sep 2020 18 %M 32961970 %F 6.085 %R 10.3390/md18090471 %X Collagen is the major fibrillar protein in most living organisms. Among the different types of collagen, type I collagen is the most abundant one in tissues of marine invertebrates. Due to the health-related risk factors and religious constraints, use of mammalian derived collagen has been limited. This triggers the search for alternative sources of collagen for both food and non-food applications. In this regard, numerous studies have been conducted on maximizing the utilization of seafood processing by-products and address the need for collagen. However, less attention has been given to marine invertebrates and their by-products. The present review has focused on identifying sea cucumber as a potential source of collagen and discusses the general scope of collagen extraction, isolation, characterization, and physicochemical properties along with opportunities and challenges for utilizing marine-derived collagen.