%0 Journal Article
%T Multidisciplinary Management of the Adverse Effects of Apremilast.
%A Daudén Tello E
%A Alonso Suárez J
%A Beltrán Catalán E
%A Blasco Maldonado C
%A Herrero Manso MC
%A Jiménez Morales A
%A Marín-Jiménez I
%A Martín-Arranz MD
%A García-Merino A
%A Porta Etessam J
%A Rodríguez-Sagrado MA
%A Rosas Gómez de Salazar J
%A Trujillo Martín E
%A Salgado-Boquete L
%J Actas Dermosifiliogr (Engl Ed)
%V 112
%N 2
%D Feb 2021
%M 32910923
暂无%R 10.1016/j.ad.2020.08.007
%X We present a series of general and specific recommendations based on pathophysiologic considerations for managing the most common adverse effects of apremilast that lead to treatment discontinuation: diarrhea, nausea, and headache. The recommendations are based on a review of the literature and the experience of a multidisciplinary team of 14 experts including dermatologists, rheumatologists, neurologists, gastroenterologists, pharmacists, and nurses. We propose a series of simple algorithms that include clinical actions and suggestions for pharmacologic treatment. The adverse effects of apremilast can be managed from a multidisciplinary approach. The purpose of optimizing management is to bring clinical benefits to patients.