%0 Journal Article %T Comparative study of biorefinery processes for the valorization of fast-growing Paulownia wood. %A Del Río PG %A Domínguez VD %A Domínguez E %A Gullón P %A Gullón B %A Garrote G %A Romaní A %J Bioresour Technol %V 314 %N 0 %D Oct 2020 %M 32622277 %F 11.889 %R 10.1016/j.biortech.2020.123722 %X In this work, valorization of Paulownia wood (PW) was proposed following several process configurations for biofuels and value-added compounds production. Firstly, autohydrolysis and ethanol-organosolv strategies were assessed separately for the fractionation of PW to enhance the enzymatic digestibility of cellulose. A third strategy focused on a sequential process (autohydrolysis and organosolv) was explored. Two temperatures were selected for the first stage of the combined process. High concentration of oligosaccharides (26.29 g/L) and high concentration of degradation products (17.21 g/L) were obtained at 210 and 230 °C, respectively. The solids obtained from both pretreatments were subjected to organosolv delignification (200 °C, 3 h and 50% ethanol) achieving delignification of 58 and 30% for the autohydrolyzed biomass at 210 °C and 230 °C, respectively. The combined process resulted in susceptible biomass able to produce 64 g/L of ethanol. Therefore, the strategies explored in this work open the possibility to build a refinery around Paulownia wood.