%0 Journal Article
%T Characteristics of genital herpes in Bilbao (Northern Spain): 12-year retrospective study.
%A Macho-Aizpurua M
%A Imaz-Pérez M
%A Álava-Menica JÁ
%A Hernández-Ragpa L
%A López-de-Munain-López MJ
%A Cámara-Pérez MM
%A Bilbao-González A
%A Díaz-de-Tuesta-Del Arco JL
%A Muñoz-Sánchez J
%A Basaras-Ibarzabal M
%A Cisterna-Cancér R
%J Enferm Infecc Microbiol Clin (Engl Ed)
%V 39
%N 5
%D 05 2021
%M 32563583
暂无%R 10.1016/j.eimc.2020.04.014
%X Herpes simplex virus type 2 (HSV-2) is the most common cause of genital herpes (GH), but genital infection by herpes simplex virus type 1 (HSV-1) is increasing. The aim of this study was to analyze and compare epidemiological characteristics of patients with GH.<BR>Retrospective study conducted from January 2004 to December 2015 in patients with GH attended at two Sexually Transmitted Diseases (STDs) medical consultation of Bilbao-Basurto Integrated Health Organisation in Northern Spain. Patient's medical history was reviewed and data of interest was analyzed.<BR>One thousand three patients (524 male and 479 female) were reviewed. HSV-2 was detected in 74%. The proportion of HSV-1 increased during the study period, significantly in men (28% in 2004-2007 vs. 50% in 2012-2015). More female than male had HSV-1 infection (56% vs. 44%). The proportion of primary infection was higher among HSV-1 compared to HSV-2 (79% vs. 21%). Among the patients with HSV-1, primary infection was higher among men (86%) and in younger than 30 years. Recurrent GH was higher among HSV-2 infections (63%). In a multivariate model older age, geographic origin outside Spain, recurrent infection, prior contact with a partner's genital herpetic lesions, previous N. gonorrhoeae infection and prostitution were significantly associated with HSV-2 infection.<BR>HSV-2 was the most common causative agent of GH, but the proportion of HSV-1 increased. Overall, antecedent of STD and sexual risk behaviors were more frequent in patients with genital HSV-2 infection.