%0 Case Reports
%T Hemoptysis as the first symptom in the diagnosis of metastatic choriocarcinoma in the third trimester of pregnancy: A case report.
%A Álvarez-Sarrado L
%A González-Ballano I
%A Herrero-Serrano R
%A Giménez-Molina C
%A Rodríguez-Solanilla B
%A Campillos-Maza JM
%J Case Rep Womens Health
%V 27
%N 0
%D Jul 2020
%M 32426244
暂无%R 10.1016/j.crwh.2020.e00211
%X <B>UNASSIGNED: </B>Choriocarcinoma is a rare neoplasm (1/40000 pregnancies). In the context of a viable pregnancy, the incidence is even lower (1/160000).<BR><B>UNASSIGNED: </B>A woman in her second pregnancy was admitted at 31 + 6 weeks of gestation with hemoptysis and abnormal vaginal bleeding. Numerous placental venous lakes, bilateral pulmonary nodules and a pleural effusion were found. Pleural fluid β-HCG levels were elevated and a brain-chest-abdominal-pelvic CT scan led to the diagnosis of a high-risk gestational trophoblastic neoplasm. A caesarean section at 32 + 1 weeks of gestation was performed. Six cycles of an EMA-CO chemotherapy regime were administered. β-HCG levels normalized after 3 cycles. Placental histopathology confirmed the presence of a gestational choriocarcinoma.<BR><B>UNASSIGNED: </B>Choriocarcinoma is a highly aggressive tumor. In high-risk tumors, combination chemotherapy is the first-line treatment, offering high remission rates. Treatment response is evaluated by monitoring blood β-HCG levels, which should be long-term.