%0 Case Reports
%T An Unusual Case of the Successful Treatment of Carbapenem-resistant Ventriculitis with Intravenous Colistin.
%A Abu Bakar A
%A Palaniandy K
%A Fadzil F
%A Jaafar AS
%A Paramasvaran S
%J Cureus
%V 12
%N 2
%D Feb 2020 27
%M 32257666
暂无%R 10.7759/cureus.7120
%X Ventriculitis is a well-documented complication of ventriculostomy, which is difficult to treat and is associated with high rates of mortality. There is a growing trend of resistance among many organisms, such as Acinetobacter baumannii, in particular, to most antibiotics with the exception of colistin. It is thought that colistin has poor blood-brain barrier penetration; therefore, in cases of ventriculitis, it is preferentially administered via the intrathecal or intraventricular route. These routes, in turn, risk introducing infections, which may perpetuate the problem. We report a case of multidrug-resistant Acinetobacter baumannii ventriculitis, which was treated successfully with intravenous colistin monotherapy.