%0 Journal Article
%T Efficacy and Safety of Endoscopic Sleeve Gastroplasty at Mid Term in the Management of Overweight and Obese Patients: a Systematic Review and Meta-Analysis.
%A de Miranda Neto AA
%A de Moura DTH
%A Ribeiro IB
%A Khan A
%A Singh S
%A da Ponte Neto AM
%A Madruga Neto AC
%A do Monte Junior ES
%A Tustumi F
%A Bernardo WM
%A de Moura EGH
%J Obes Surg
%V 30
%N 5
%D May 2020
%M 32107706
%F 3.479
%R 10.1007/s11695-020-04449-9
%X <B>BACKGROUND: </B>Endoscopic sleeve gastroplasty (ESG) has emerged as a promising technique in endoscopic bariatric and metabolic therapies (EBMTs). We aimed to perform a systematic review and meta-analysis to provide an update on its efficacy and safety.<BR><B>METHODS: </B>This is a systematic review and meta-analysis was performed following the PRISMA guidelines. MEDLINE, Cochrane, EMBASE, and LILACS were searched to identify the studies related to ESG.<BR><B>RESULTS: </B>Eleven studies with a total of 2170 patients were included. The average BMI pre-ESG was 35.78 kg/m2. Pooled mean %TWL observed at 6, 12, and 18 months was 15.3%, 16.1%, and 16.8% respectively. Pooled mean %EWL at 6, 12, and 18 months was 55.8%, 60%, and 73% respectively. No procedure-related mortality was reported.<BR><B>CONCLUSIONS: </B>ESG is a safe and effective procedure for primary obesity therapy with promising short- and mid-term results.