%0 Journal Article
%T New entry to the enantioselective formation of substituted cyclohexenes bearing an all-carbon quaternary stereogenic center.
%A Komine K
%A Urayama Y
%A Hosaka T
%A Fukuda H
%A Hatakeyama S
%A Ishihara J
%J Chirality
%V 32
%N 3
%D 03 2020
%M 31957912
%F 2.183
%R 10.1002/chir.23173
%X Enantioselective formation of cyclohexene derivatives bearing an all-carbon quaternary stereogenic center is described. The racemic cyclohexenes are readily transformed to chiral substituted cyclohexenes in good yield with excellent enantioselectivity and diastereoselectivity by a palladium-mediated deracemization. The resulting products are promising synthetic intermediates of biologically active natural products. This protocol provides us with a new entry to the concise and scalable synthesis of multifunctionalized compounds.