%0 Journal Article
%T [Expert consensus from "Frontier Workshop on Pathogen Surveillance, Detecting and Tracing, and Vaccine Development"].
%A  
%J Zhonghua Yu Fang Yi Xue Za Zhi
%V 54
%N 1
%D Jan 2020 6
%M 31914568
暂无%R 10.3760/cma.j.issn.0253-9624.2020.01.010
%X Focusing on the current challenges and opportunities of China National Infectious Disease Surveillance Network (CNIDS), the exploration and development of pathogen detecting and tracing technologies, and the key issues in vaccine development, 48 experts from the disease control and prevention centers; research institutes, universities and hospitals launched an in-depth discussion on October 24-27, 2019, and reached the following consensus. (1) CNIDS needs to coordinate operational activities and to integrate data across governmental departments in order to build a human-centered and life-cycle based disease monitoring and health managing system. (2) In addition to standardize and further strengthen pathogen culturing and isolating techniques, it is desired to develop multi-targeted, ultra-sensitive, high-specific, high-throughput, digitalized and easy-to-use techniques for pathogen detections and pathobionts analyses. (3) The rapid development of pathogen tracing technologies calls to facilitate the formulation of a more efficient pathogen-tracing system by integrating technologies from genomics, bioinformatics and microbiology.(4) To strengthen the basic researches to support new vaccine developments, to explore vaccination strategies and to unfold the post-marketing evaluation on vaccines. Finally, experts proposed and discussed possiblecountermeasures and suggestions tackling with those challenges.<BR>来自疾病控制、高校科研院所、医疗机构的48位专家于2019年10月24—27日围绕我国传染病监测网络面临的挑战与机遇，病原微生物检测与溯源技术的探索和未来发展需求，以及疫苗研发面临的关键问题等内容展开了深入的讨论，并达成共识：（1）我国传染病监测网络亟须跨部门进行业务和数据整合，建设并完善以人为核心的全生命周期疾病监测与健康管理系统；（2）传统病原分离培养技术仍需进一步规范和加强，病原微生物检测技术亟须发展多靶标、超灵敏、高特异、便捷化和数字化的高中通量的新技术，并发展基于致病共栖菌谱新靶标的疾病诊断新技术；（3）亟须建立基因组学、生物信息学、微生物学等多学科交叉的溯源技术体系；（4）疫苗研发亟须相关基础研究支撑，并需加强疫苗接种策略和上市后评价与评估策略的研究。同时根据以上问题提出了专家建议。.