%0 Journal Article
%T The Asia-Pacific Society of Cardiology (APSC) Expert Committee Consensus Recommendations for Assessment of Suspected Acute Coronary Syndrome Using High-Sensitivity Cardiac Troponin T in the Emergency Department.
%A Tan WCJ
%A Inoue K
%A AbdelWareth L
%A Giannitsis E
%A Kasim S
%A Shiozaki M
%A Aw TC
%A Cheng F
%A Dung HT
%A Li YH
%A Lim SH
%A Lukito AA
%A Than M
%A Chu FY
%A Devasia T
%A Lee CC
%A Phrommintikul A
%A Youn JC
%A Chew DP
%J Circ J
%V 84
%N 2
%D 01 2020 24
%M 31852863
%F 3.35
%R 10.1253/circj.CJ-19-0874
%X The Asia-Pacific Society of Cardiology (APSC) high-sensitivity troponin T (hs-TnT) consensus recommendations and rapid algorithm were developed to provide guidance for healthcare professionals in the Asia-Pacific region on assessing patients with suspected acute coronary syndrome (ACS) using a hs-TnT assay. Experts from Asia-Pacific convened in 2 meetings to develop evidence-based consensus recommendations and an algorithm for appropriate use of the hs-TnT assay. The Expert Committee defined a cardiac troponin assay as a high-sensitivity assay if the total imprecision is ≤10% at the 99th percentile of the upper reference limit and measurable concentrations below the 99th percentile are attainable with an assay at a concentration value above the assay's limit of detection for at least 50% of healthy individuals. Recommendations for single-measurement rule-out/rule-in cutoff values, as well as for serial measurements, were also developed. The Expert Committee also adopted similar hs-TnT cutoff values for men and women, recommended serial hs-TnT measurements for special populations, and provided guidance on the use of point-of-care troponin T devices in individuals suspected of ACS. These recommendations should be used in conjunction with all available clinical evidence when making the diagnosis of ACS.