%0 Case Reports
%T False-negative result of serum cryptococcal antigen lateral flow assay in an HIV-infected patient with culture-proven cryptococcaemia.
%A Borges MASB
%A Araújo Filho JA
%A Soares RBA
%A Vidal JE
%A Turchi MD
%J Med Mycol Case Rep
%V 26
%N 0
%D Dec 2019
%M 31737475
暂无%R 10.1016/j.mmcr.2019.10.009
%X The detection of cryptococcal capsular antigen (CrAg) is very sensitive and specific, however false-negative results have been reported, mostly in cerebrospinal fluid. We report the case of an HIV-infected patient with CD4 = 42 cells/mL, asthenic, negative serum CrAg lateral flow assay (LFA) and culture-proven cryptococcaemia. Despite the high accuracy of LFA, false-negative result is possible. Careful clinical evaluation and close follow-up are relevant.