%0 Journal Article
%T Aorto-cardiac fistula etiology, presentation, and management: A systematic review.
%A Foster TJ
%A Amin AH
%A Busu T
%A Patel K
%A Farjo P
%A Hallak AA
%A Ali N
%A Alkhouli M
%J Heart Lung
%V 49
%N 3
%D May 2020 0
%M 31735456
%F 3.149
%R 10.1016/j.hrtlng.2019.11.002
%X Aorto-cardiac fistulae are a rare but increasingly reported entity, and data are scarce.
The authors performed a systematic review of ACFs to characterize the underlying etiology, clinical presentation, and compare outcomes of treatment strategies.
3,733 publications were identified in the search. Of those, 292 studies including 300 patients were included. Etiology of ACFs was 38% iatrogenic, 25% infectious, 14% traumatic, and 15% due to other causes. Most patients (74%) presented with heart failure. Common locations were aortic-right atrium (37%), and aortic-pulmonary artery (25%). The majority of patients (71%) were treated surgically, while 13% were treated percutaneously, and 16% were treated conservatively. Patients who were managed conservatively had a higher mortality than those treated with invasive closure (53% vs. 12% vs. 3%, p = <0.00001).
This systematic review sheds light on this highly morbid condition. Once recognized, fistula closure appears to be superior to conservative management.