%0 Comparative Study
%T Survival outcomes of mucosal melanoma in the USA.
%A Al-Haseni A
%A Vrable A
%A Qureshi MM
%A Mathews S
%A Pollock S
%A Truong MT
%A Sahni D
%J Future Oncol
%V 15
%N 34
%D Dec 2019
%M 31724885
%F 3.674
%R 10.2217/fon-2019-0465
%X Background: Mucosal melanomas (MM) arise within the lining of the gastrointestinal (GI), genitourinary (GU) and head and neck (HN) systems. Method: A retrospective analysis of the National Comprehensive Database identified 4,961 MM patients. Primary objective was to compare survival outcomes across the different locations. Results: Overall survival for GI melanomas was significantly shorter than HN and GU melanomas. Median survival (95% confidence interval) was 19.5 (18.0-21.5), 26.4 (24.9-28.3), and 43.9 (38.8-47.8), months for GI, HN and GU cases, respectively (p<0.0001). Conclusion: This is the largest study of MM in a US based population, demonstrating worse overall survival for GI MM in comparison to HN and GU melanomas.