%0 Journal Article
%T [Legionella spp: An update].
%A Cattan S
%A Thizy G
%A Michon A
%A Arlet JB
%A Lanternier F
%A Lebeaux D
%A Jarraud S
%A Pouchot J
%A Lafont E
%J Rev Med Interne
%V 40
%N 12
%D Dec 2019
%M 31703951
%F 0.885
%R 10.1016/j.revmed.2019.08.007
%X Legionella-related disease is caused by an intracellular bacteria mainly living in water. Contamination results from inhalation of Legionella sp containing aerosolized water. Main risk factors are tobacco, immunodeficiency, and advanced age. Antigenuria is the cornerstone of the diagnosis. Immunocompromised patients, more commonly infected with non pneumophilaLegionella, present negative antigenuria, and culture and PCR are essential for the diagnosis. Legionnaires' disease may be severe, especially in elderly and/or immunocompromised patients. Mortality rate varies from 10 % in the general population to 50 % in intensive care. Treatment is based on macrolides or fluoroquinolones. Antibiotic resistance is very rare.