%0 Case Reports
%T Berlin Heart EXCOR® pediatric ventricular assist device in a patient with Sotos syndrome: a case report.
%A Gravino R
%A Limongelli G
%A Petraio A
%A Masarone D
%A Russo MG
%A Maiello C
%A Verrengia M
%A De Paulis D
%A Pacileo G
%J J Med Case Rep
%V 13
%N 1
%D Aug 2019 31
%M 31470900
暂无%R 10.1186/s13256-019-2190-9
%X <B>BACKGROUND: </B>Berlin Heart EXCOR® pediatric ventricular assist device is a mechanical circulatory support device currently used in pediatric patients. Sotos syndrome is a well-described multiple anomaly syndrome characterized by overgrowth, distinctive craniofacial appearance, cardiac abnormalities, and variable learning disabilities.<BR><B>METHODS: </B>We describe a 7-year-old female Caucasian child with classic Sotos syndrome features subjected to implantation of Berlin Heart EXCOR® pediatric biventricular assist device mechanical support. A heart transplant was carried out after a support time of 459 days. After 5 years of follow-up, our patient is clinically stable and the performance of the transplanted heart is excellent.<BR><B>CONCLUSIONS: </B>This case confirms that Berlin Heart EXCOR® pediatric ventricular assist device can provide satisfactory and safe circulatory support for children with end-stage heart diseases, even in those with Sotos syndrome. The syndrome is not a contraindication to implantation, since the complications are the same as those observed in patients without the syndrome and the prognosis is not affected by the disease.