%0 Journal Article
%T [The clinical application of gelatin sponge in prevention and treatment of chylous leakage during left neck lymph node dissection].
%A Ma LJ
%A Wang SX
%J Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
%V 33
%N 8
%D Aug 2019
%M 31446737
暂无%R 10.13201/j.issn.1001-1781.2019.08.021
%X Objective:The aim of this study is to explore the preventive and therapeutic effects of gelatin sponge on the occurrence and development of chylous leakage by combining the biological characteristics of gelatin sponge with the mechanism of left neck lymph node dissection. Method: Eight hundred and twenty-eight patients who underwent left neck lymph node dissection in our department were retrospectively analyzed, 568 of whom underwent routine chylous leakage prevention and treatment （group A）, 260 underwent gelatin sponge tamponade fixation. The prevention and treatment of chyle leakage （group B） were analyzed. Result:Twenty-six cases of chyle leakage occurred in group A and 8 cases of chyle leakage occurred in group B. The incidence of chyle leakage in group B （3.1%） was not significantly different from that in group A （4.6%）. However, the incidence of chyle leakage within three days after operation was better than that in group A, and the amount of chyle leakage was significantly less than that in group A. The time of improving chylous leakage by positive pressure bandaging was better than that of group A, with statistical significance. Conclusion:Gelatin sponge packing can not reduce the occurrence of chyle leakage, but can delay the occurrence time of chyle leakage and reduce the amount of chyle leakage. It has a certain clinical value in the active treatment of chyle leakage.<BR>目的：利用明胶海绵生物学特性结合左颈淋巴结清扫术中乳糜漏发生机制，探讨明胶海绵在乳糜漏发生、发展中的防治作用。 方法：828例行左颈淋巴结清扫术患者，其中568例行常规乳糜漏防治（A组），260例行明胶海绵填塞固定乳糜漏防治（B组），分析术后乳糜漏的发生情况。 结果：A组26例（4.6%）发生乳糜漏，B组8例（3.1%）发生乳糜漏，2组差异无统计学意义；术后B组3 d内出现乳糜漏量明显少于A组，经积极加压包扎治疗有效改善乳糜漏的时间优于A组，2组差异有统计学意义。 结论：采用明胶海绵填塞术区不能减少乳糜漏发生，但可延缓乳糜漏的发生时间，减少乳糜漏量，在积极治疗已发生的乳糜漏上具有一定的临床应用价值。.