%0 Case Reports
%T Neuropathic diabetic foot ulcers treated with cerium dioxide nanoparticles: A case report.
%A Kobyliak N
%A Abenavoli L
%A Kononenko L
%A Kyriienko D
%A Spivak M
%J Diabetes Metab Syndr
%V 13
%N 1
%D Jan 2019 0
%M 30641702
暂无%R 10.1016/j.dsx.2018.08.027
%X Wound healing in diabetes is frequently impaired and its treatment remains a challenge. The ability of topical application of cerium (Ce) dioxide nanoparticles (CNPs) to accelerate wound healing in an animal model provides a rationale to develop this technology for use in humans affected by traumatic injury, diabetes and burns. We first described a case report of successful topical treatment of neuropathic diabetic foot ulcers with novel gel containing CNPs. The CNPs has bacteriostatic activity, anti-inflammatory properties and can penetrated into the wound tissue and reduced oxidative damage therefore protect regenerative tissue, suggesting a therapeutic potential for topical treatment of diabetic foot ulcers.