%0 Case Reports %T Therapeutic Options in Diffuse Large B-Cell Lymphoma - A Retrospective Study and Review of the Literature. %A Patrascu AM %A Nacea J %A Patrascu Ş %A Goganau A %A Delcea F %A Mogoanta L %A Rotaru I %J Curr Health Sci J %V 43 %N 3 %D Jul-Sep 2017 %M 30595888 暂无%R 10.12865/CHSJ.43.03.15 %X The aim of this retrospective study was to assess the differences between standard R-CHOP and other Rituximab-associated chemotherapy (R-miniCHOP and R-CHOEP) regimens in terms of survival and potential adverse effects. The six-month survival outcomes of 94 diffuse large B-cell lymphomas (DLBCL) patients indicated no statistical difference between overall survival and disease-free survival in the two subgroups. The biological response to therapy (blood count, LDH levels) was similar in both subgroups. Despite having different clinical indications, R-miniCHOP and R-CHOEP provide viable therapeutic alternatives to the standard R-CHOP regimen.