%0 Journal Article %T New ADCY3 Variants Dance in Obesity Etiology. %A Tian Y %A Peng B %A Fu X %J Trends Endocrinol Metab %V 29 %N 6 %D 06 2018 %M 29454745 %F 10.586 %R 10.1016/j.tem.2018.02.004 %X The genetic etiology for obesity-related traits remains elusive. Recent studies link novel ADCY3 variants to obesity and diabetes, and identify an important role of ADCY3-mediated signaling at neuronal primary cilia in the predisposition of obesity. These findings provide new information on obesity etiology and suggest potential anti-obesity therapeutic strategies.