%0 Case Reports
%T Haploidentical hematopoietic stem cell transplantation for a case with X-linked chronic granulomatous disease.
%A Zhou L
%A Dong LJ
%A Gao ZY
%A Yu XJ
%A Lu DP
%J Pediatr Transplant
%V 21
%N 1
%D Feb 2017
%M 27885760
%F 1.551
%R 10.1111/petr.12861
%X CGD is a rare primary immunodeficiency with high mortality rates when treated conventionally, especially for the X-chromosome-linked form. HSCT is the only curative therapy for CGD; however, haploidentical transplantation in CGD is rare. Here, we report a case of X-linked CGD treated successfully by haploidentical HSCT. The patient showed a positive result with full donor chimerism, good quality of life, and the absence of recurrent infectious diseases at follow-up (68 months). Thus, haploidentical HSCT may serve as an acceptable treatment approach for patients who have CGD, but no HLA-matched related or unrelated donor.