%0 Case Reports
%T [Clinical analyses of the diagnosis and treatment of invasive fungal rhinosinusitis: report of 14 cases].
%A Shi GG
%A Shi L
%A Zhang ZY
%A Wan YZ
%A Li B
%A Yu L
%A Zhang EP
%A Ju HS
%A He MQ
%A Ji HZ
%J Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
%V 51
%N 8
%D Aug 2016 7
%M 27625123
暂无%R 10.3760/cma.j.issn.1673-0860.2016.08.001
%X <B>OBJECTIVE: </B>Through the retrospective analysis of the clinical data in 14 cases of invasive fungal rhinosinusitis (IFRS), the clinical characteristics, diagnosis and treatment of this disease were evaluated.<BR><B>METHODS: </B>Fourteen clinically confirmed cases of IFRS since January 2008 to October 2015 were evaluated.collected, the clinical features, diagnosis, treatment and prognosis were analyzed to obtain a more comprehensive understanding for clinical reference. Fourteen patients were confirmed by pathological examination as IFRS, including 9 cases of aspergillus, 4 cases of mucor, and 1 case of rhinocerebral zygomycosis; including 5 cases of acute IFRS, 9 cases of chronic IFRS. All patients were treated with endoscopic surgery and intravenous antifungal therapy.<BR><B>RESULTS: </B>Nine cases of chronic IFRS (including 1 case of mucor, 7 cases of aspergillus and 1 case of rhinocerebral zygomycosis) were cured, but the vision loss, diplopia or blindness, hard palate perforation remained. Five cases of acute IFRS included 3 cases of mucor and 2 cases of aspergillus. Among the 3 cases of mucor, 2 cases were died and 1 case was cured. Among the 2 cases of aspergillus, 1 patient was cured and the other patient died of electrolyte disorder after discharge from hospital.<BR><B>CONCLUSIONS: </B>Patients with IFRS usually have diabetes. After the active surgical cleaning of lesion tissue and the systematic antifungal treatment with adequate dosage, these patients would have a better result. IFRS caused by mucor is ofen dangerous.