%0 Journal Article
%T Chiral Primary Amine/Palladium Dual Catalysis for Asymmetric Allylic Alkylation of β-Ketocarbonyl Compounds with Allylic Alcohols.
%A Zhou H
%A Zhang L
%A Xu C
%A Luo S
%J Angew Chem Int Ed Engl
%V 54
%N 43
%D Oct 2015 19
%M 26337681
%F 16.823
%R 10.1002/anie.201505946
%X An efficient dual catalytic system composed of a chiral primary amine and a palladium complex was developed to promote the direct asymmetric allylic alkylation (AAA) of β-ketocarbonyl compounds. In particular, the synergistic dual catalytic system enabled the AAA reaction of challenging acyclic aliphatic ketones, such as β-ketocarbonyl compounds and 1,3-diketones.