%0 Case Reports
%T Primary testicular Ph-positive B lymphoblastic lymphoma: an unusual presentation and review.
%A Zhu J
%A Zhang S
%A Zhu L
%A Li X
%A Wang Y
%A Duan Y
%A Huang W
%J Cancer Biol Ther
%V 16
%N 8
%D 2015
%M 26147907
%F 4.875
%R 10.1080/15384047.2015.1056412
%X Primary testicular B-lymphoblastic lymphoma is a rare entity. Primary testicular Ph-positive B lymphoblastic lymphoma was not reported before. We reported a 27-year-old man with primary testicular Ph-positive B lymphoblastic lymphoma, for which fluorescent in-situ hybridization (FISH) for the Philadelphia chromosome was not performed at the initial hospitalization. The patient showed manifestation of Ph-positive acute lymphoblastic leukemia at relapse. In this report, we reviewed the current literature about primary testicular B-lymphoblastic lymphoma, Ph-positive lymphoma and Ph-positive clone evolution. This report has 3 meanings. First: This is first report on primary testicular Ph-positive B lymphoblastic lymphoma. Second: This shows the importance of cytogenics for lymphoma treatment. Third: This implies Philadelphia-positive subclone evolution.