%0 Case Reports
%T Lipiodol injections for optimization of target volume delineation in a patient with a second tumor of the oropharynx: A case report.
%A Haderlein M
%A Merten R
%A Stojanovic A
%A Speer S
%A Scherl C
%A Fietkau R
%A Ott OJ
%J Strahlenther Onkol
%V 191
%N 8
%D Aug 2015
%M 26040498
%F 4.033
%R 10.1007/s00066-015-0856-9
%X <B>BACKGROUND: </B>Lipiodol injections were administered in the head and neck area to improve gross tumor volume (GTV) definition for small-volume re-irradiation of a 63-year-old previously irradiated patient with a second tumor of the oropharynx in the posterior wall with longitudinal ligament infiltration (cT4cN0cM0).<BR><B>METHODS: </B>The patient had dialysis-depending renal failure. On diagnostic computed tomography (CT), which was performed with intravenous contrast agent, the tumor in the oropharynx was not detectable. Because of dialysis-depending renal failure comorbidity, no contrast agent was applied in the planning CT and in the diagnostic magnetic resonance imaging (MRI) study. In each cross-sectional imaging study performed, the GTV, especially in craniocaudal extensions, was not safely delineable. Therefore, craniocaudal tumor margins were pharyngoscopically marked with Lipiodol injections, an iodine-containing contrast agent.<BR><B>RESULTS: </B>In a second planning CT, the GTV could be defined with the help of the Lipiodol marks and small-volume re-irradiation was performed. No Lipiodol-associated side effects occurred in the patient.<BR><B>CONCLUSIONS: </B>In the present case, the use of Lipiodol injections at the tumor margins facilitated the definition of the GTV.