%0 Journal Article
%T Adenoid cystic carcinoma of the larynx: a report of six cases with review of the literature.
%A Liu W
%A Chen X
%J Acta Otolaryngol
%V 135
%N 5
%D May 2015
%M 25743246
%F 1.698
%R 10.3109/00016489.2014.990583
%X <B>CONCLUSIONS: </B>Adenoid cystic carcinoma (ACC) in the larynx is an extremely rare entity. Although the 5-year disease-specific survival rates for laryngeal ACC are high, distant metastasis might occur up to more than 5 years post treatment. Therefore patients with ACC require long-term follow-up.<BR><B>OBJECTIVE: </B>To summarize the characteristics of laryngeal ACC by analyzing six cases in a single center.<BR><B>METHODS: </B>This was a retrospective analysis of six patients with laryngeal ACC who were treated in Beijing Tongren Hospital between 1998 and 2013.<BR><B>RESULTS: </B>The mean age at diagnosis was 44 years, ranging from 15 to 61 years. Dyspnea was the most common complaint. All patients underwent combined-modality treatment with surgical resection and external beam radiation. The range of follow-up time varied from 1 to 7 years (median 5 years). Follow-up inspections indicated that none of them had local or regional recurrence. Distant metastasis occurred in 33.7% (2/6) of the patients, with one lung metastasis 5 years after operation and one liver metastasis 4 years after operation.