%0 Journal Article
%T Innate γδT17 cells convert cancer-elicited inflammation into immunosuppression through myeloid-derived suppressor cells.
%A Yan J
%A Huang J
%J Oncoimmunology
%V 3
%N 8
%D 2014
%M 25610744
暂无%R 10.4161/21624011.2014.953423
%X Chronic inflammation has been linked to cancer development and metastasis. We have recently demonstrated that γδ T cells are the major cellular source of IL-17 (γδT17) and accumulation of γδT17 cells correlates with human colorectal cancer progression through recruitment and expansion of myeloid-derived suppressor cells, thus converting tumor-elicited inflammation into immunosuppression.