%0 Journal Article %T Vessel based delineation guidelines for the elective lymph node regions in breast cancer radiation therapy - PROCAB guidelines. %A Verhoeven K %A Weltens C %A Remouchamps V %A Mahjoubi K %A Veldeman L %A Lengele B %A Hortobagyi E %A Kirkove C %J Radiother Oncol %V 114 %N 1 %D Jan 2015 %M 25466373 %F 6.901 %R 10.1016/j.radonc.2014.11.008 %X OBJECTIVE: A national project to improve the quality of breast radiation therapy was started, named PROCAB (PROject on CAncer of the Breast). One of the objectives was to reach a national consensus guideline for the delineation of the regional lymph node areas in breast radiation therapy.
METHODS: The realization of the new guidelines was a step by step process that started with multiple expert meetings where the existing guidelines were analyzed and the delineations of the lymph node regions were performed together with a surgeon, specialized in the anatomy of the drainage of the breast.
RESULTS: The delineation guidelines are vessel-based. Since the occurrence of pathological lymph nodes is typically around the veins, the cranial and caudal borders of all different nodal regions are based on a 5mm margin around the veins, except for the parasternal lymph node area. Compared to the existing guidelines there are some major changes.
CONCLUSIONS: With this project a national as well as a European (ESTRO) consensus guideline for the delineation of the regional lymph node areas in breast RT is reached. The new delineation atlas is vessel-based and no longer field-based.