%0 Journal Article
%T Five polyostotic conditions that general orthopedic surgeons should recognize (or should not miss).
%A Muthusamy S
%A Conway SA
%A Temple HT
%J Orthop Clin North Am
%V 45
%N 3
%D Jul 2014
%M 24975767
%F 2.771
%R 10.1016/j.ocl.2014.04.004
%X General orthopedic surgeons frequently encounter patients with conditions affecting multiple bones. It is important to recognize common polyostotic diseases. This article describes five polyostotic conditions: Multipe Enchondromatosis (Ollier Disease and Maffucci syndrome), Multiple Hereditary Exostosis (Diaphyseal Aclasis), Fibrous Dysplasia (McCune-Albright syndrome and Mazabraud syndrome), Paget's Disease of bone (Osteitis Deformans), and Skeletal Metastases. This is a survey of the clinical, pathologic and radiographic features that assist in diagnosing these conditions. Also, an overview of the laboratory findings, treatment, follow-up, and prognosis is presented. Recognizing these diseases will aid in prompt and accurate diagnosis and appropriate referral and therapy.