%0 Journal Article
%T Clinical practice guideline on diagnosis and treatment of hyponatraemia.
%A Spasovski G
%A Vanholder R
%A Allolio B
%A Annane D
%A Ball S
%A Bichet D
%A Decaux G
%A Fenske W
%A Hoorn EJ
%A Ichai C
%A Joannidis M
%A Soupart A
%A Zietse R
%A Haller M
%A van der Veer S
%A Van Biesen W
%A Nagler E
%A  
%J Eur J Endocrinol
%V 170
%N 3
%D Mar 2014
%M 24569125
%F 6.558
%R 10.1530/EJE-13-1020
%X Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic. The prevalence of hyponatraemia in widely different conditions and the fact that hyponatraemia is managed by clinicians with a broad variety of backgrounds have fostered diverse institution- and speciality-based approaches to diagnosis and treatment. To obtain a common and holistic view, the European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA), represented by European Renal Best Practice (ERBP), have developed the Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia as a joint venture of three societies representing specialists with a natural interest in hyponatraemia. In addition to a rigorous approach to methodology and evaluation, we were keen to ensure that the document focused on patient-important outcomes and included utility for clinicians involved in everyday practice.