%0 Journal Article
%T Lack of association between HTR4 gene polymorphisms and schizophrenia in case-control and family-based samples.
%A Hirata Y
%A Souza RP
%A Lieberman JA
%A Meltzer HY
%A Kennedy JL
%J Psychiatry Res
%V 175
%N 1
%D Jan 2010 30
%M 19892407
%F 11.225
%R 10.1016/j.psychres.2009.08.005
%X Previous studies have found haplotypic association of HTR4 variants and schizophrenia. Examining case-control pairs, G-G of rs7713886 was associated with schizophrenia risk. The A-A-G-G-G-A-A rs9325104-rs1422636-rs7715569-rs6873382-rs7711800-rs10078551-rs2068190 haplotype was overrepresented in the schizophrenia cases. The associations were no longer significant after corrections for multiple comparisons. No association was found in the family sample.