%0 Journal Article %T The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). %A Greaves J %A Prescott GR %A Gorleku OA %A Chamberlain LH %J Mol Membr Biol %V 26 %N 1 %D Jan 2009 %M 19115144 暂无%R 10.1080/09687680802620351 %X The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.