%0 Journal Article
%T Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions.
%A Tung ET
%A Ma HW
%A Cheng C
%A Lim BL
%A Wong KB
%J Protein Pept Lett
%V 15
%N 3
%D 2008
%M 18336361
%F 1.927
%R 10.2174/092986608783744216
%X Phytases play important roles in agricultural and feed industries. In this study, the stability of a beta-propeller phytase, PhyL, from Bacillus licheniformis was successfully improved by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions. Our results suggest that Gly-->Ala substitution is a more promising strategy to improve protein stability.