%0 Case Reports
%T Type I CD36 deficiency associated with metabolic syndrome and vasospastic angina: a case report.
%A Kamiya M
%A Nakagomi A
%A Tokita Y
%A Yasutake M
%A Kusama Y
%A Takayama M
%A Takano T
%J J Cardiol
%V 48
%N 1
%D Jul 2006
%M 16886497
%F 2.974
%X A 54-year-old man was admitted to our hospital for evaluation of chest pain occurring at rest in the morning. ST segment depression was observed during a treadmill exercise test. Coronary angiography identified spontaneous spasm of the proximal right coronary artery, and right coronary obstruction was improved from 90% to about 50% stenosis after intracoronary administration of nitroglycerin. Myocardial iodine-123 beta-methyl-p-iodophenyl-pentadecanoic acid uptake was absent, but thallium-201 uptake during single photon emission computed tomography was normal, and neither platelet nor monocyte expression of the CD36 molecule was observed, indicating type I CD36 deficiency. High blood pressure, elevated plasma triglyceride and fasting plasma glucose levels, and low high-density lipoprotein values suggested metabolic syndrome. The final diagnosis was type I CD 36 deficiency associated with metabolic syndrome and vasospastic angina.